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KMID : 1151920200020010041
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Chronobiology in Medicine
2020 Volume.2 No. 1 p.41 ~ p.44
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Early Onset Depression Has Different Characteristics from Middle-Aged Depression in Terms of Circadian Rhythm
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Jeong Jaeg-Won
Lee Yu-Jin
Cho Chul-Hyun
Lee Heon-Jeong
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Abstract
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Objective: The aim of this study was to identify the unique biological and circadian rhythmic characteristics of patients with early-onset depression compared to patients with middle-age-onset depression.
Methods: A total of 240 subjects were recruited in the study and divided into three groups: healthy young individuals, patients with early-onset depression, and middle-aged patients with unipolar depression. Patients then filled out questionnaires related to biological rhythm disturbances, mood symptoms, diurnal preference, and seasonality.
Results: Patients with early-onset depression had significantly different clinical features in terms of mood disorders, diurnal preference, and biological rhythm disturbances compared to middle-aged patients with unipolar depression.
Conclusion: Results of this study suggest that early-onset depression is different from middle-age-onset unipolar depression but similar to bipolar disorder.
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KEYWORD
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Circadian rhythm, Depression, Bipolar disorder
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